Allison Abbot reports in Nature on whether the difficulty in finding the genes responsible for mental illness reflect the complexity of the genetics or the poor definitions of psychiatric disorders?
Researchers are convinced that variations in DISC1 and many other genes can scramble the intricate and as yet inscrutable processes by which brain circuits develop and function, and that this scrambling leaves some people at greater risk of psychiatric problems than others. Even if one or more risk genes are present, external stress or some other event may decide whether and what symptoms are triggered.
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 Source: Nature
