We live in a world filled with material wealth, live longer and healthier lives, and yet anxiety, stress, unhappiness, and depression have never been more common. What are the driving forces behind these interlinked global epidemics? In this series, Professor Mark Williams (Wellcome Trust Principal Research Fellow at Oxford University) and Dr Danny Penman discuss the recent scientific advances that have radically altered our understanding of depression and related disorders. Also discussed is the latest treatments and therapies that are offering hope to those suffering from depression. Professor Williams co-developed Mindfulness-Based Cognitive Therapy (MBCT), a treatment for anxiety, stress and depression that is at least as effective as drugs at preventing new episodes of depression. It’s now one of the preferred treatments for depression recommended by the UK’s National Institute for Health and Clinical Excellence. The same technique, based upon an ancient form of meditation, can also help us cope more effectively with the relentless demands of our increasingly frantic world. Professor Williams and Dr Penman co-authored the bestselling book Mindfulness: Finding Peace in a Frantic World.

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Kok et al. conducted a study on remitted patients with at least 2 previous episodes of depression, randomized to mobile Cognitive Therapy in addition to treatment as usual.Results showed that residual depressive symptoms showed a small but statistically significant decrease in the intention-to-treat group over 3 months in the mobile CT group relative to the treatment as usual group.
Residual depressive symptoms after remission showed a more favourable course over 3 months in the mobile CT group compared to the treatment as usual group . These results are a first indication that mobile CT in addition to treatment as usual is effective in treating
recurrently depressed patients in remission. However, demonstration of its long-term effectiveness and replication remains necessary.
