From today’s ( Sept 16th,2010) Corrections page in the New York Times:
An article on Aug. 10 about spinal fluid tests in Alzheimer’s research left the incorrect impression that the test can predict the disease with 100 percent accuracy in all patients. (That impression was reinforced by the headline.) In fact, the test was found to be as much as 100 percent accurate in identifying a signature level of abnormal proteins in patients with memory loss who went on to develop Alzheimer’s — not in identifying patients who “are on their way” to developing the disease.
The article also misinterpreted an element of the researchers’ findings. Among a group of patients who had memory loss and developed Alzheimer’s within five years, every one had protein levels associated with the disease five years before; it was not the case that “every one of those patients with the proteins developed Alzheimer’s within five years.”
And the article misstated the source from which the finding of 100 percent accuracy was drawn. It came from a separate set of patients that the researchers examined to validate the protein signature they had identified in an initial group. (In the initial group, as the article noted, nearly every person with Alzheimer’s had the signature protein levels.) (Go to Article)